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Brefeldin A(BFA or Cyanein and Decumbin)

Brefeldin A(BFA or Cyanein and Decumbin)

Product Details:

75 USD ($)/Milligram

Brefeldin A(BFA or Cyanein and Decumbin) Price And Quantity

  • 75 USD ($)/Milligram
  • 60.00 - 115.00 USD ($)/Milligram
  • 5

Brefeldin A(BFA or Cyanein and Decumbin) Trade Information

  • Shanghai China
  • Telegraphic Transfer (T/T)
  • 600 Per Month
  • 3 Days
  • Within a certain price range free samples are available
  • COA 10mg/bottle
  • North America Western Europe Central America Australia South America Asia
  • All India

Product Description

Product name:Brefeldin A(BFA; Cyanein; Decumbin)




Description: Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus. Brefeldin A is also an autophagy and mitophagy inhibitor. Brefeldin A is a CRISPR/Cas9 activator. Brefeldin A inhibits HSV-1 and has anti-cancer activity.

Brefeldin A (BFA) is a natural fungal metabolite which has been used extensively to study intracellular transport by vesicles or endosomes. Early studies demonstrated that BFA reversibly interferes with protein trafficking and secretion mediated by the Golgi apparatus and endoplasmic reticulum. BFA directly and reversibly inhibits Sec7 domain-containing guanine-exchange factors which are necessary for ADP-ribosylation factor activation associated with vesicular transport (IC50 = 10 M). BFA is used to study endosomal trafficking and function in cells of plants as well as those of fungi, invertebrates, and vertebrates.

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