Product name:Tauroursodeoxycholic acid/TUDCA
CAS:14605-22-2
MF:C26H45NO6S
MW:499.7
Description: Tauroursodeoxycholate inhibits human cholangiocarcinoma growth via Ca2, PKC, and MAPK-dependent pathways.
It can be used in the treatment of cholesterol gallstones. Tauroursodeoxycholic acid is also being investigated for use in several conditions such as Primary Biliary Cirrhosis(PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis.
Tauroursodeoxycholic acid is the more hydrophilic form of ursodeoxycholic acid, which is naturally produced in the body. In patients with properly functioning gallbladders, both of these bile acids inhibit liver cholesterol secretion and synthesis as well as intestinal cholesterol absorption allowing for the promotion of cholesterol gallstone dissolution. The main mechanisms supporting possible Neuroprotective effects of TUDCA include the prevention of apoptosis.