Product Name:Lidocaine hydrochloride(Lidocaine HCl)
Synonym:Lidocaine hydrochloride;Lidocaine HCl;73-78-9;LIGNOCAINE HYDROCHLORIDE;Lidociane Hydrochloride;Lidocaie Hydrochloride;Lithium Claviate
Description:Lidocaine hydrochloride was synthesized by Lofgren and Lundquist in 1943, and was clinically introduced in 1948. It remains one of the most widely used local anaesthetics. It can be administered parenterally for a peripheral nerve block (PNB), intravenously, or applied topically at strengths of 2 4. The addition of epinephrine 1:200 000 to 1:100 000 slows the vascular absorption of lidocaine and prolongs its effects.
Lidocaine hydrochloride is characterized by strong penetration, strong dispersion, rapidly onset. The anesthetic performance is twice that of procaine and the toxicity is1. There is an anesthetic effect after 5 minutes treatments, and anesthesia can last 1 to 1.5 hours, 50 longer than procaine. The drug is effective on the heart of the disease or arrhythmia caused by cardiac glycoside, but on the supraventricular tachycardia is poor. This product is fast and oral ineffective, with short duration, and often used as intravenous administration.