Description:Bremelanotide, also known as PT-141, is a melanocortin peptide hormone. Bremelanotide (PT-141) was
developed from Melanotan II (MT-2) and can be regarded as a derivate from MT-2.
Bremelanotide (PT-141) is regarded as the only synthetic aphrodisiac. Studies have shown Bremelanotide to be effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). Unlike Viagra and other related medications (PDE5s), PT-141 does not act upon the vascular system, but directly through the nervous system (hypothalamus) to increase desire.
Viagra, Cials and Levitra are not considered aphrodisiacs as they do not have any direct effect on the libido. However, treatment with PDE5 inhibitors and PT-141 are known to have a synergistic effect.
Application:PT-141 is a potential remedy for the treatment of sexual dysfunction; specifically,male erectile dysfunction.
Studies have shown that PT-141 does not act on the vascular system like former compounds, but allegedly works by activating melanocortin receptors in the brain, therefore helping increase ones sexual stimulation. PT-141 is a melanocortin based peptide that has shown effectiveness in clinical studies on both male and female rats. Male rats have shown erectile response with doses as low as 1-2mgs whereas most female rats have shown positive results with higher doses around 2-3mgs. While the dosage requirements tend to be higher for female rats, the observable results in female rats tend to be stronger.