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Tween 80 (polysorbate 80)

Tween 80 (polysorbate 80)

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Product Description

Product Name:Tween 80(polysorbate 80)

Synonym:Tween 80;polysorbate 80;9005-65-6;Tween 80 fandachem;glycol;armotanpmo-20;atlox1087;

Molecular Formula:C24H44O6

Formula Weight:428.600006103516

CAS No.:9005-65-6


Description:Tween 80, commonly known as polysorbate 80, is a synthetic compound that is widely applied in a variety of fields, including foods, medicines, and cosmetics. In food production, it is commonly used as a defoamer for the fermenting process of some wines and as a emulsifier in ice-cream or puddings to keep the creamy texture without separating. Tween 80 is also extensively applied in pharmaceutical industry, where it can be found in some vaccines, vitamins and supplements. It is an effective excipient to stabilize aqueous formulations of medications for parenteral administration and to improve the consistency of gel capsules, thus to make pills disperse in the stomach. Besides, it commonly serve as a surfactant and solubilizer in the production of soaps and cosmetics, which is effective to help dissolve ingredients and make products look creamier and more attractive. In laboratory, it is occasionally  used for a test to identify the phenotype of a strain or isolate, such as mycobacteria.

TWEEN 80 is a polyethylene sorbitol ester, with a calculated molecular weight of 1,310 daltons, assuming 20 ethylene oxide units, sorbitol, and 1 oleic acid as the primary fatty acid.

Tweens are a series of nonionic surfactants derived from sorbitan esters. They are soluble or dispersible in water but differ widely in organic and oil solubilities. TWEEN 80 has been widely used in biochemical applications including: solubilizing proteins, isolating nuclei from cells in culture,5 growing of tubercule bacilli,6 and emulsifying and dispersing substances in medicinal and food products. It has little or no activity as an anti-bacterial agent1 except it has been shown to have an adverse effect on the antibacterial effect of methyl paraben and related compounds. Polysorbates have been reported to be incompatible with alkalis, heavy metal salts, phenols, and tannic acid. They may reduce the activity of many preservatives.


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