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Sancycline CAS:808-26-4

Sancycline CAS:808-26-4

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Product name:Sancycline

CAS:808-26-4

MF:C21H22N2O7

MW:414.41

Description: Sancycline is a semisynthetic tetracycline antibiotic that is more active than tetracycline (Item No. 14328) against 339 strains of anaerobic bacteria (average MIC90s = 1 and 32 g/ml, respectively). Sancycline is active against tetracycline-resistant E. coli, S. aureus, and E. faecalis strains with MICs ranging from 0.06 to 1 g/ml. In vivo, sancycline is active against S. aureus in mice with ED50 values of 0.46 and 0.6 mg/kg for intravenous and subcutaneous administration, respectively.

Sancycline is a tetracycline bacteriostatic antibiotic which also binds to the Tet repressor protein (TetR).

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