Product name:Pemirolast potassium(TWT-8152; BMY 26517)
CAS:100299-08-9
MF:C10H7KN6O
MW:266.3
Description: Pemirolast potassium (TWT-8152) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent. Target: Histamine H1 Receptor Pemirolast potassium (TWT-8152) is a new oral, nonbronchodilator antiallergy medication that is being evaluated for the therapy of asthma . Pemirolast potassium (TWT-8152) inhibits chemical mediator release from tissue mast cells and is also shown to inhibit the release of peptides including substance P, Pemirolast potassium (TWT-8152) reduces kaolin intake by inhibition of substance P release in rats . Pemirolast potassium (TWT-8152) potently attenuates paclitaxel hypersensitivity reactions through inhibition of the release of sensory neuropeptides in rats . Pemirolast potassium (TWT-8152) potassium is used for the treatment of allergic conjunctivitis and prophylaxis for pulmonary hypersensitivity reactions to drugs such as paclitaxel.