
Product Name:Melengestrol acetate
Synonym:Melengestrol acetate;2919-66-6;MGA;NSC-70968;Aids125382;Aids-125382;Malengestrol acetate;Melengestrol Acerate;Melengesterol acetate;
Molecular Formula:C25H32O4
Formula Weight:396.52
CAS No.:2919-66-6
Appearance:Light Yellow Powder
Usage:Orally active progestational steroid. Progestogen; growth promotant.
Description:Melengestrol acetate (INN, USAN),sometimes abbreviated as MGA, is a steroidal progestin and antineoplastic agent. It is not approved for use in humans, and is instead used as a feed additive to promote growth in cattle, a purpose it is licensed for in the United States and Canada. It is an acetate ester of melengestrol, which in contrast, is not used in either animals or humans.
Application:
The use of steroid hormone analogues in animals used for human consumption has been a source ofinternational debate for many years. In the European Union, a total ban of anabolic agents for growth promotion in food animals has been in place since 1988 on the bases of unknown or poorly demonstrated food safety (Stephany 2001). After a review of 17 scientific studies by the Scientific Committee on Veterinary Measures Relating to Public Health, the European Commission concluded that hormonally-treated meat poses a risk to consumers (SCVPH 2002).
Conversely, in Canada and the USA, certain synthetic and natural anabolic steroid hormones are approved for use under controlled regulations (Stephany 2001). Interestingly, after a review of the same 17 studies, Health Canada concluded that residues in beef pose no undue risk to human health, provided the drugs are used and administered appropriately.