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Fexofenadine hydrochloride(Allegra or MDL-16455 hydrochloride )

Fexofenadine hydrochloride(Allegra or MDL-16455 hydrochloride )

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Product name:Fexofenadine hydrochloride(Allegra;MDL-16455 hydrochloride; Terfenadine carboxylate hydrochloride)

CAS:153439-40-8

MF:C32H40ClNO4

MW:538.13

Description: Fexofenadine hydrochloride (trade name: Allegra) belongs to a second-generation antihistamine pharmaceutical drug. It is mainly used for the treatment of allergy symptoms including watery eyes, hay fever, nasal congestion, urticaria, runny nose, itching eyes/nose, sneezing, hives, and itching. It is a kind of selectively peripheral H1 blocker. Its mechanism of action in vivo is through preventing the histamine-mediated activation of the H1 receptors, thus alleviating the symptoms related to allergy. Compared to the first-generation antihistamine drug, it is less prone to penetrate the blood-brain barrier, reducing the possibility to cause side effects such as drowsiness.

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