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Estradiol CAS:57-91-0

Estradiol CAS:57-91-0

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Product name:Estradiol

CAS:57-91-0

MF:C18H24O2

MW:272.39

Description: Estradiol is an endogenous estrogenic hormone receptor (ER) agonist (Ki values are 0.12 and 0.13 nM for ER and ER respectively). Also high affinity ligand at membrane estrogen GPR30 receptors. -Estradiol is an activator of PI 3-kinase.

Estradiol (17 -estradiol, -Estradiol, E2, 17 -Oestradiol) is a human sex hormone and steroid, and the primary female sex hormone. Estradiol upregulates IL-6 expression through the estrogen receptor (ER ) pathway.


17 -Estradiol is the major estrogen secreted by the premenopausal ovary.This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.

-Estradiol is used to study cell differentiation and transformations (tumorigenicity).


Estradiol is a white or milky white ordorless crystalline powder. It is soluble in dioxane and acetone, slightly soluble in ethanol, and insoluble in water.

Estradiol is the intermediate between estradiol valerate and estradiol benzoate, and it is a type of estrogen drug. It can be used to treat uterine functional bleeding, primary amenorrhea, menopausal syndrome, and prostate cancer. Estradiol can promote and adjust the normal growth of female sex organs and secondary sex characteristics, promote mammary duct maturation and growth, and aid in posseting. Estradiol can also be used in biochemical research.

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