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Dalfopristin(Quinupristin or RP54476) CAS:112362-50-2

Dalfopristin(Quinupristin or RP54476)  CAS:112362-50-2

Product Details:

68 USD ($)/Milligram
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Price And Quantity

  • 68 USD ($)/Milligram
  • 10 Milligram
  • 35.00 - 90.00 USD ($)/Milligram

Product Description

Product name:Dalfopristin/Quinupristin/RP54476

CAS:112362-50-2

MF:C34H50N4O9S

MW:690.85

Description: Dalfopristin is a semi-synthetic analogue of ostreogyrcin A (virginiamycin M, pristinamycin IIA, streptogramin A) formed by addition of diethylaminoethylthiol to the 2-pyrroline group of ostreogyrcin, followed by oxidation to the sulphone. The structural changes provide a more hydrophobic compound with a readily ionisable group for generating a salt. Dalfopristin is used commercially in synergistic combination with quinupristin (70:30). There is little published data on the synthesis, biological or antibiotic activity of dalfopristin alone, however the combination product is highly effective, including activity against antibiotic resistant strains.

Dalfopristin is a semi-synthetic analogue of ostreogrycin A (virginiamycin M, pristinamycin IIA, streptogramin A) formed by addition of diethylaminoethylthiol to the 2-pyrroline group of ostreogrycin, followed by oxidation to the sulfone. The structural changes provide a more hydrophobic compound with a readily ionisable group for generating a salt. Dalfopristin is used commercially in synergistic combination with quinupristin (70:30). There is little published data on the synthesis, biological or antibiotic activity of dalfopristin alone, however the combination product is highly effective, including activity against antibiotic resistant strains.

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