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Andarine (GTx-007)

Andarine (GTx-007)

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Product Description

Product Name:Andarine

Synonym:Andarine;401900-40-1;S-4;Andarine;S4;MK-2866;MK2866;GTx-007

Molecular Formula:C19H18F3N3O6

Formula Weight:441.36

CAS No.:401900-40-1

Appearance:White Crystalline Powder


Description:Andarine (GTx-007, S-4) is an investigational selective androgen receptor modulator (SARM) developed by GTX, Inc for treatment of conditions such as muscle wasting, osteoporosis and benign prostatic hypertrophy,using the non-steroidal androgen antagonist bicalutamide as a lead compound.

Andarine is an orally active partial agonist for androgen receptors. It is less potent in both anabolic and androgenic effects than other SARMs. In an animal model of benign prostatic hypertrophy, andarine was shown to reduce prostate weight with similar efficacy to finasteride, but without producing any reduction in muscle mass or anti-androgenic side effects.This suggests that it is able to competitively block binding of dihydrotestosterone to its receptor targets in the prostate gland, but its partial agonist effects at androgen receptors prevent the side effects associated with the anti-androgenic drugs traditionally used for treatment of BPH

S-4 belongs to a class of chemicals known as SARMS or selective androgen receptor modulators. Like typical androgens, SARMS bind to the androgen receptor however SARMS create selective anabolic activity.Compared to testosterone and other anabolic steroids and pro hormones, the advantage of SARMS such as S-4 is that they do not have androgenic activity in non-skeletal-muscle tissues.

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