Description:Adrenosterone(11-OXO) is a steroid hormone with weak androgenic effect first isolated in 1936 from the adrenal cortex. Adrenosterone occurs in trace amounts in humans along with most mammals as well as in larger amounts in fish, where this is a precursor to the primary androgen, 11-ketotestosterone.
Adrenosterone(11-OXO) has demonstrated to be converted into 11-ketotestosterone in humans, which plays a part in adrenosterone's androgenic effects.
Adrenosterone(11-OXO)'s main action can it be lowers cortisol levels. Cortisol could be the main catabolic (muscle-eating) hormone and it also promotes fat gain. Cortisol and testosterone also work in an inverse relationship, really at high point cortisol levels lower testosterone.
Adrenosterone(11-OXO) acts as a competitive inhibitor, preventing cortisone from attaching to the 11b-hydroxysteroid dehydrogenase type I reductase. By competing at the receptor, it keeps cortisone from attaching and converting to cortisol with the enzyme. Adrenosterone is found naturally within the body and is released by the adrenal glands. The body uses it as a way to help regulate cortisol levels.